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Why Flu can be Fatal?
Posted on June 13th, 2010 under General Health. Post a comment
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Why the flu causes a simple runny nose in some people and others can be severe and even fatal? The key is the virus’s ability to paralyze the immune system, according to a study at Children’s Hospital of Philadelphia (USA) issued in the latest issue of the Journal of Leukocyte Biology.
In reaching this conclusion Kathleen Sullivan and his team recruited a group of children with severe influenza and analyzed the levels of cytokines, compounds secreted by cells of the immune system that act as messengers to recruit other cells to help defend the body when an infection occurs.
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Analysis revealed that although the concentration of these molecules in blood was normal in critically ill children flu response cytokine receptors was much weaker.
The results indicate that in these patients the flu virus causes paralysis of the immune system, reducing its ability to defend against other germs. And their immune paralysis may be long lasting.
This process, Sullivan adds, may explain why 25% of children who die from influenza die from serious secondary bacterial infections such as pneumonia. [photo by everydayhealth.com]
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